GATA2 mutation in long stand Mycobacterium kansasii infection, myelodysplasia and MonoMAC syndrome: a case-report

• Main Authors: Daniela Palheiro Mendes- (Author), Francianne Gomes Andrade (Author), Gustavo Borges (Author), Filipe V. dos Santos-Bueno (Author), Iracema F. Vieira (Author), Luana Kelly M. da S. da Rocha (Author), Daniella A. Mendes- (Author), Rosely M. Zancopé-Oliveira (Author), Rodrigo T. Calado (Author), Maria S. Pombo- (Author)
• Format: Book
• Published: BMC, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background GATA2 is a transcription factor that is a critical regulator of gene expression in hematopoietic cells. GATA2 deficiency presents with multi-lineage cytopenia, mycobacterial, fungal and viral infections. Patients with GATA2 mutation have a high risk of developing myelodysplastic...