Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects

Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects

Background: Immunogenicity refers to the inherent ability of a molecule to stimulate an immune response. Aggregates are one of the major risk factors for the undesired immunogenicity of therapeutic antibodies (Ab) and may ultimately result in immune-mediated adverse effects. For Ab delivered by inha...

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Main Authors: Thomas Sécher (Author), Elsa Bodier-Montagutelli (Author), Christelle Parent (Author), Laura Bouvart (Author), Mélanie Cortes (Author), Marion Ferreira (Author), Ronan MacLoughlin (Author), Guy Ilango (Author), Otmar Schmid (Author), Renaud Respaud (Author), Nathalie Heuzé-Vourc'h (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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