Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant

• Main Authors: Lázaro Moreira Marques Neto (Author), Nicholas Zufelato (Author), Ailton Antônio de Sousa-Júnior (Author), Monalisa Martins Trentini (Author), Adeliane Castro da Costa (Author), Andris Figueiroa Bakuzis (Author), André Kipnis (Author), Ana Paula Junqueira-Kipnis (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metal-based nanoparticles (NPs) stimulate innate immunity; however, they have never been demonstrated to be capable of aiding the generation of specific cellular immune responses. Therefore, our objective was to evaluate whether iron oxide-based NPs have adjuvant properties in generating cellular Th...