Exposure to excess phenobarbital negatively influences the osteogenesis of chick embryos

• Main Authors: Yu Yan (Author), Xin Cheng (Author), Ren-hao Yang (Author), He Li (Author), Jian-long Chen (Author), Zheng-lai Ma (Author), Guang Wang (Author), Manli Chuai (Author), Xuesong Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phenobarbital is an antiepileptic drug that is widely used to treat epilepsy in a clinical setting. However, a long term of phenobarbital administration in pregnant women may produce side effects on embryonic skeletogenesis. In this study, we aim to investigate the mechanism by which phenobarbital t...