A Novel CD48-Based Analysis of Sepsis-Induced Mouse Myeloid-Derived Suppressor Cell Compartments

• Main Authors: Bei Jia (Author), Chenchen Zhao (Author), Guoli Li (Author), Yaxian Kong (Author), Yaluan Ma (Author), Qiuping Wang (Author), Beibei Wang (Author), Hui Zeng (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous subset of cells that expands dramatically in many disease states and can suppress T-cell responses. MDSCs mainly include monocytic and granulocytic subpopulations that can be distinguished in mice by the expression of Ly6G and Ly6C cell su...