Effects of 5-Fluorouracil on the Expression of Epigenetic Enzymes and Promoter Methylation of Selected Genes in Monolayer and Spheroid Cultures of Colorectal Cancer Cells

Background: Emerging evidence suggests that epigenetic mechanisms contribute to 5-fluorouracil (5-FU) resistance in colorectal cancer (CRC). However, there is limited research on the direct impact of 5-FU on epigenetic alterations in CRC. This study aimed to investigate how 5-FU treatment affects th...

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Autores principales: Maryam Niknam (Autor), Masoumeh Varedi (Autor), Mozhdeh Zamani (Autor), Pooneh Mokarram (Autor), Fakhraddin Naghibalhossaini (Autor)
Formato: Libro
Publicado: Tabriz University of Medical Sciences, 2024-01-01T00:00:00Z.
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