Chronic Treatment with Fluoxetine Induces Sex-Dependent Analgesic Effects and Modulates HDAC2 and mGlu2 Expression in Female Mice

• Main Authors: Magda Zammataro (Author), Sara Merlo (Author), Massimo Barresi (Author), Carmela Parenti (Author), Huijuan Hu (Author), Maria A. Sortino (Author), Santina Chiechio (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gender and sex differences in pain recognition and drug responses have been reported in clinical trials and experimental models of pain. Among antidepressants, contradictory results have been observed in patients treated with selective serotonin reuptake inhibitors (SSRIs). This study evaluated sex...