Females present higher dose‐adjusted drug concentrations of metoprolol and allopurinol/oxypurinol than males

• Main Authors: Jessica Hindi (Author), Marc‐Olivier Pilon (Author), Maxime Meloche (Author), Grégoire Leclair (Author), Essaïd Oussaïd (Author), Isabelle St‐Jean (Author), Martin Jutras (Author), Marie‐Josée Gaulin (Author), Ian Mongrain (Author), David Busseuil (Author), Jean Lucien Rouleau (Author), Jean‐Claude Tardif (Author), Marie‐Pierre Dubé (Author), Simon deDenus (Author)
• Format: Book
• Published: Wiley, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Females present a higher risk of adverse drug reactions. Sex‐related differences in drug concentrations may contribute to these observations but they remain understudied given the underrepresentation of females in clinical trials. The aim of this study was to investigate whether anthropomet...