Enhancing the anticancer potential of metformin: fabrication of efficient nanospanlastics, in vitro cytotoxic studies on HEP-2 cells and reactome enhanced pathway analysis

• Главные авторы: Shereen Nader Raafat (Автор), Sara Abd El Wahed (Автор), Noha M. Badawi (Автор), Mona M. Saber (Автор), Maha R.A. Abdollah (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2023-12-01T00:00:00Z.
• Предметы: article
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Metformin (MET), an oral antidiabetic drug, was reported to possess promising anticancer effects. We hypothesized that MET encapsulation in unique nanospanlastics would enhance its anticancer potential against HEP-2 cells. Our results showed the successful fabrication of Nano-MET spanlastics (d = 23...