MLN-4760 Induces Oxidative Stress without Blood Pressure and Behavioural Alterations in SHRs: Roles of <i>Nfe2l2</i> Gene, Nitric Oxide and Hydrogen Sulfide

MLN-4760 Induces Oxidative Stress without Blood Pressure and Behavioural Alterations in SHRs: Roles of <i>Nfe2l2</i> Gene, Nitric Oxide and Hydrogen Sulfide

Reduced angiotensin 1-7 bioavailability due to inhibition of angiotensin-converting enzyme 2 (ACE2) may contribute to increased mortality in hypertensive individuals during COVID-19. However, effects of ACE2 inhibitor MLN-4760 in brain functions remain unknown. We investigated the selected behaviour...

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Main Authors: Michal Kluknavsky (Author), Andrea Micurova (Author), Martina Cebova (Author), Ezgi Şaman (Author), Sona Cacanyiova (Author), Iveta Bernatova (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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