Targeting AGTPBP1 inhibits pancreatic cancer progression via regulating microtubules and ERK signaling pathway

Abstract Background AGTPBP1 is a cytosolic carboxypeptidase that cleaves poly-glutamic acids from the C terminus or side chains of α/β tubulins. Although its dysregulated expression has been linked to the development of non-small cell lung cancer, the specific roles and mechanisms of AGTPBP1 in panc...

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Autores principales: Ding-zhong Li (Autor), Zhe-yu Yang (Autor), Asi leng (Autor), Qian Zhang (Autor), Xiao-dong Zhang (Autor), Yan-chao Bian (Autor), Rui Xiao (Autor), Jian-jun Ren (Autor)
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Publicado: BMC, 2024-08-01T00:00:00Z.
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