Targeting AGTPBP1 inhibits pancreatic cancer progression via regulating microtubules and ERK signaling pathway

• Main Authors: Ding-zhong Li (Author), Zhe-yu Yang (Author), Asi leng (Author), Qian Zhang (Author), Xiao-dong Zhang (Author), Yan-chao Bian (Author), Rui Xiao (Author), Jian-jun Ren (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background AGTPBP1 is a cytosolic carboxypeptidase that cleaves poly-glutamic acids from the C terminus or side chains of α/β tubulins. Although its dysregulated expression has been linked to the development of non-small cell lung cancer, the specific roles and mechanisms of AGTPBP1 in panc...