Glycoprotein YKL-40 Levels in Plasma Are Associated with Fibrotic Changes on HRCT in Asbestos-Exposed Subjects

• Auteurs principaux: Tuija Väänänen (Auteur), Lauri Lehtimäki (Auteur), Katriina Vuolteenaho (Auteur), Mari Hämäläinen (Auteur), Panu Oksa (Auteur), Tuula Vierikko (Auteur), Ritva Järvenpää (Auteur), Jukka Uitti (Auteur), Hannu Kankaanranta (Auteur), Eeva Moilanen (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2017-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

YKL-40 is a chitinase-like glycoprotein produced by alternatively activated macrophages that are associated with wound healing and fibrosis. Asbestosis is a chronic asbestos-induced lung disease, in which injury of epithelial cells and activation of alveolar macrophages lead to enhanced collagen pro...