Protective versus pathologic pre-exposure cytokine profiles in dengue virus infection.
BACKGROUND:Hyperendemic circulation of all four types of dengue virus (DENV-1-4) has expanded globally, fueling concern for increased incidence of severe dengue. While the majority of DENV infections are subclinical, epidemiologic studies suggest that type-cross-reactive immunity can influence disea...
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Public Library of Science (PLoS),
2018-12-01T00:00:00Z.
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