A modified choline-deficient, ethionine-supplemented diet reduces morbidity and retains a liver progenitor cell response in mice

• Główni autorzy: Adam M. Passman (Autor), Robyn P. Strauss (Autor), Sarah B. McSpadden (Autor), Megan L. Finch-Edmondson (Autor), Ken H. Woo (Autor), Luke A. Diepeveen (Autor), Roslyn London (Autor), Bernard A. Callus (Autor), George C. Yeoh (Autor)
• Format: Książka
• Wydane: The Company of Biologists, 2015-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The choline-deficient, ethionine-supplemented (CDE) dietary model induces chronic liver damage, and stimulates liver progenitor cell (LPC)-mediated repair. Long-term CDE administration leads to hepatocellular carcinoma in rodents and lineage-tracing studies show that LPCs differentiate into function...