Causality Evaluation of Drug-Induced Liver Injury in Newborns and Children in the Intensive Care Unit Using the Updated Roussel Uclaf Causality Assessment Method

• Main Authors: Ling Ye (Author), Zeying Feng (Author), Longjian Huang (Author), Chengjun Guo (Author), Xiong Wu (Author), Li He (Author), Wei Tan (Author), Yi Wang (Author), Xuehong Wu (Author), Biwen Hu (Author), Tong Li (Author), Guoping Yang (Author), Guo Chengxian (Author), Qingnan He (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Drug-induced liver injury (DILI) is a common adverse reaction in the clinic; however, there are relatively few reports of DILI in critically ill newborns and children. Making use of the Pediatric Intensive Care database (PIC), this study identifies which drugs are related to DILI in neonate...