The KOUNCIL Consortium: From Genetic Defects to Therapeutic Development for Nephronophthisis

• 主要な著者: Kirsten Y. Renkema (著者), Rachel H. Giles (著者), Marc R. Lilien (著者), Philip L. Beales (著者), Ronald Roepman (著者), Machteld M. Oud (著者), Heleen H. Arts (著者), Nine V. A. M. Knoers (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Nephronophthisis (NPH) is the most common monogenic cause of renal failure in children. Treatment options are limited to dialysis and transplantation. Therapeutics to significantly delay or prevent end-stage renal disease (ESRD) in children are currently not available. In the Dutch-Anglo KOUNCIL (Ki...