The KOUNCIL Consortium: From Genetic Defects to Therapeutic Development for Nephronophthisis

• Main Authors: Kirsten Y. Renkema (Author), Rachel H. Giles (Author), Marc R. Lilien (Author), Philip L. Beales (Author), Ronald Roepman (Author), Machteld M. Oud (Author), Heleen H. Arts (Author), Nine V. A. M. Knoers (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nephronophthisis (NPH) is the most common monogenic cause of renal failure in children. Treatment options are limited to dialysis and transplantation. Therapeutics to significantly delay or prevent end-stage renal disease (ESRD) in children are currently not available. In the Dutch-Anglo KOUNCIL (Ki...