Elucidating the role of Rgs2 expression in the PVN for metabolic homeostasis in mice

• Main Authors: Yue Deng (Author), Jacob E. Dickey (Author), Kenji Saito (Author), Guorui Deng (Author), Uday Singh (Author), Jingwei Jiang (Author), Brandon A. Toth (Author), Zhiyong Zhu (Author), Leonid V. Zingman (Author), Jon M. Resch (Author), Justin L. Grobe (Author), Huxing Cui (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: RGS2 is a GTPase activating protein that modulates GPCR-Gα signaling and mice lacking RGS2 globally exhibit metabolic alterations. While RGS2 is known to be broadly expressed throughout the body including the brain, the relative contribution of brain RGS2 to metabolic homeostasis remains...