Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro

• Main Authors: Hongbo Liu (Author), Fei Ye (Author), Qi Sun (Author), Hao Liang (Author), Chunmei Li (Author), Siyang Li (Author), Roujian Lu (Author), Baoying Huang (Author), Wenjie Tan (Author), Luhua Lai (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

COVID-19 has become a global pandemic and there is an urgent call for developing drugs against the virus (SARS-CoV-2). The 3C-like protease (3CLpro) of SARS-CoV-2 is a preferred target for broad spectrum anti-coronavirus drug discovery. We studied the anti-SARS-CoV-2 activity of S. baicalensis and i...