Macrophage alternative activation confers protection against lipotoxicity-induced cell death

• Váldodahkkit: Lingling Dai (Dahkki), Prerna Bhargava (Dahkki), Kristopher J. Stanya (Dahkki), Ryan K. Alexander (Dahkki), Yae-Huei Liou (Dahkki), David Jacobi (Dahkki), Nelson H. Knudsen (Dahkki), Alexander Hyde (Dahkki), Matthew R. Gangl (Dahkki), Sihao Liu (Dahkki), Chih-Hao Lee (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2017-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Objective: Alternative activation (M2) of adipose tissue resident macrophage (ATM) inhibits obesity-induced metabolic inflammation. The underlying mechanisms remain unclear. Recent studies have shown that dysregulated lipid homeostasis caused by increased lipolysis in white adipose tissue (WAT) in t...