Photochemical Restoration of Light Sensitivity in the Degenerated Canine Retina

• Main Authors: Sergei Nikonov (Author), Natalia Dolgova (Author), Raghavi Sudharsan (Author), Ivan Tochitsky (Author), Simone Iwabe (Author), Jose-Manuel Guzman (Author), Russell N. Van Gelder (Author), Richard H. Kramer (Author), Gustavo D. Aguirre (Author), William A. Beltran (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Photopharmacological compounds such as azobenzene-based photoswitches have been shown to control the conductivity of ionic channels in a light-dependent manner and are considered a potential strategy to restore vision in patients with end-stage photoreceptor degeneration. Here, we report the effects...