Integrated 16S rRNA sequencing and metabolomics analysis to investigate the antidepressant role of Yang-Xin-Jie-Yu decoction on microbe-gut-metabolite in chronic unpredictable mild stress-induced depression rat model

• Main Authors: Xing-Qiu Liang (Author), Peng-Yu Mai (Author), Hui Qin (Author), Sen Li (Author), Wen-Juan Ou (Author), Jian Liang (Author), Jing Zhong (Author), Ming-Kun Liang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Our goals were to evaluate the antidepressant efficacy of Yang-Xin-Jie-Yu Decoction (YXJYD) in Chronic Unpredictable Mild Stress (CUMS)-induced depression rat model and to investigate the underlying mechanisms.Design: We used CUMS-induced depression rat model to evaluate whether oral adm...