Case Report: p40phox deficiency underlying pediatric-onset systemic lupus erythematosus

• Main Authors: Alejandro Nieto-Patlán (Author), Natalia S. Fernández Dávila (Author), Yuqing Wang (Author), Michelle Zelnick (Author), Eyal Muscal (Author), Martha Curry (Author), James R. Lupski (Author), Steven M. Holland (Author), Bo Yuan (Author), Douglas B. Kuhns (Author), Tiphanie P. Vogel (Author), Ivan K. Chinn (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionSystemic lupus erythematosus is a multi-faceted autoimmune disorder of complex etiology. Pre-pubertal onset of pediatric systemic lupus erythematosus (pSLE) is uncommon and should raise suspicion for a genetic driver of disease. Autosomal recessive p40phox deficiency is a rare immunologi...