The Chinese Herbal Prescription JieZe-1 Inhibits Membrane Fusion and the Toll-like Receptor Signaling Pathway in a Genital Herpes Mouse Model

• Main Authors: Qianni Duan (Author), Tong Liu (Author), Cong Huang (Author), Qingqing Shao (Author), Yonggui Ma (Author), Wenjia Wang (Author), Tianli Liu (Author), Jun Sun (Author), Jianguo Fang (Author), Guangying Huang (Author), Zhuo Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chinese herbal prescription JieZe-1 is effective for genital herpes with no visible adverse effects clinically. It showed an excellent anti-HSV-2 effect in vitro. However, its mechanism of anti-HSV-2 effect in vivo remains unclear. This study was designed to evaluate the anti-HSV-2 effect of JieZe-1...