Mechanism Underlying the Protective Effect of Tempol and Nω-Nitro-l-arginine Methyl Ester on Acoustic Injury: Possible Involvement of c-Jun N-Terminal Kinase Pathway and Connexin26 in the Cochlear Spiral Ligament

• Автори: Reiko Nagashima (Автор), Taro Yamaguchi (Автор), Hajime Tanaka (Автор), Kiyokazu Ogita (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2010-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

There is evidence that reactive oxygen species (ROS) are formed in the cochlea during acoustic injury. However, very little is known about the involvement of ROS signals in the spiral ligament (SL) during such injury. The purpose of this study was to determine the effect of the multifunctional antio...