Expression patterns of STAT3, ERK and estrogen-receptor α are associated with development and histologic severity of hepatic steatosis: a retrospective study

• Autori principali: Euno Choi (Autore), Won Kim (Autore), Sae Kyung Joo (Autore), Sunyoung Park (Autore), Jeong Hwan Park (Autore), Yun Kyung Kang (Autore), So-Young Jin (Autore), Mee Soo Chang (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2018-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Hepatic steatosis renders hepatocytes vulnerable to injury, resulting in the progression of preexisting liver disease. Previous animal and cell culture studies implicated mammalian target of rapamycin (mTOR), signal transducer and activator of transcription-3 (STAT3), extracellul...