Sympathetic overdrive and unrestrained adipose lipolysis drive alcohol-induced hepatic steatosis in rodents

• Main Authors: Chunxue Zhou (Author), Henry H. Ruiz (Author), Li Ling (Author), Giulia Maurizi (Author), Kenichi Sakamoto (Author), Claudia G. Liberini (Author), Ling Wang (Author), Adrien Stanley (Author), Hale E. Egritag (Author), Sofia M. Sanz (Author), Claudia Lindtner (Author), Mary A. Butera (Author), Christoph Buettner (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Hepatic steatosis is a key initiating event in the pathogenesis of alcohol-associated liver disease (ALD), the most detrimental organ damage resulting from alcohol use disorder. However, the mechanisms by which alcohol induces steatosis remain incompletely understood. We have previously f...