Chlorogenic acid promotes angiogenesis and attenuates apoptosis following cerebral ischaemia-reperfusion injury by regulating the PI3K-Akt signalling

• Main Authors: Yong Fan (Author), Yongkun Li (Author), Yongkai Yang (Author), Kunzhe Lin (Author), Qingqiang Lin (Author), Shenghui Luo (Author), Xiaohui Zhou (Author), Qun Lin (Author), Fan Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Chlorogenic acid (CGA) has good antioxidant effects, but its explicit mechanism in cerebral ischaemia-reperfusion injury is still uncertain.Objective We studied the effect of CGA in human brain microvascular endothelial cells (HBMECs) under OGD/R damage.Materials and methods HBMECs in 4 grou...