Chlorogenic acid promotes angiogenesis and attenuates apoptosis following cerebral ischaemia-reperfusion injury by regulating the PI3K-Akt signalling

• Egile Nagusiak: Yong Fan (Egilea), Yongkun Li (Egilea), Yongkai Yang (Egilea), Kunzhe Lin (Egilea), Qingqiang Lin (Egilea), Shenghui Luo (Egilea), Xiaohui Zhou (Egilea), Qun Lin (Egilea), Fan Zhang (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Context Chlorogenic acid (CGA) has good antioxidant effects, but its explicit mechanism in cerebral ischaemia-reperfusion injury is still uncertain.Objective We studied the effect of CGA in human brain microvascular endothelial cells (HBMECs) under OGD/R damage.Materials and methods HBMECs in 4 grou...