Inhibitors of Human ABCG2: From Technical Background to Recent Updates With Clinical Implications
The ATP-binding cassette transporter G2 (ABCG2; also known as breast cancer resistance protein, BCRP) has been suggested to be involved in clinical multidrug resistance (MDR) in cancer like other ABC transporters such as ABCB1 (P-glycoprotein). As an efflux pump exhibiting a broad substrate specific...
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2019-03-01T00:00:00Z.
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