Human parathyroid hormone fragment stimulates the de novo synthesis of prostaglandin endoperoxide synthase in chick calvaria

• Ngā kaituhi matua: Chin-Yuh Yang (Author), Ching-Liang Meng (Author), Patrick Y- K. Wong (Author)
• Hōputu: Pukapuka
• I whakaputaina: Hindawi Limited, 1993-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

The human parathyroid hormone N-terminal fragment [hPTH-(1-34)] increases the conversion of exogenous unsaturated fatty acids to prostaglandins (PGs) in calvarial homogenates. Enzyme activities were completely blocked by indomethacin (5 × 10−7 M), a PG synthase inhibitor, and actinomycin D (5 μM), a...