Metastatic Melanomas Express Inhibitory Low Affinity Fc Gamma Receptor and Escape Humoral Immunity

• Prif Awduron: Joel F. G. Cohen-Solal (Awdur), Lydie Cassard (Awdur), Emilie M. Fournier (Awdur), Shannon M. Loncar (Awdur), Wolf Herman Fridman (Awdur), Catherine Sautès-Fridman (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Hindawi Limited, 2010-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Our research, inspired by the pioneering works of Isaac Witz in the 1980s, established that 40% of human metastatic melanomas express ectopically inhibitory Fc gamma receptors (Fc𝛾RIIB), while they are detected on less than 5% of primary cutaneous melanoma and not on melanocytes. We demonstrated tha...