Estimation of glomerular filtration rate for drug dosing in patients with very high or low body mass index

• Main Authors: Erik M. Donker (Author), Pierre Bet (Author), Azam Nurmohamed (Author), Erik Serné (Author), George Louis Burchell (Author), Allon N. Friedman (Author), Antoine Bouquegneau (Author), Sandrine Lemoine (Author), Natalie Ebert (Author), Massimo Cirillo (Author), Michiel A. vanAgtmael (Author), Imke H. Bartelink (Author)
• Format: Book
• Published: Wiley, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract An accurate estimated glomerular filtration rate (eGFR) is essential in drug dosing. This study demonstrates the limitations of indexed (ml/min/1.73 m2) and de‐indexed (ml/min) eGFR based drug dosing in patients with obesity or underweight. This systematic study aimed to determine the most...