3-Hydroxyphthalic Anhydride-Modified Chicken Ovalbumin as a Potential Candidate Inhibits SARS-CoV-2 Infection by Disrupting the Interaction of Spike Protein With Host ACE2 Receptor

• Main Authors: Taizhen Liang (Author), Jiayin Qiu (Author), Xiaoge Niu (Author), Qinhai Ma (Author), Chenliang Zhou (Author), Pei Chen (Author), Qiao Zhang (Author), Meiyun Chen (Author), Zifeng Yang (Author), Shuwen Liu (Author), Lin Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The global spread of the novel coronavirus SARS-CoV-2 urgently requires discovery of effective therapeutics for the treatment of COVID-19. The spike (S) protein of SARS-CoV-2 plays a key role in receptor recognition, virus-cell membrane fusion and virus entry. Our previous studies have reported that...