Chitosan-Coated Hydroxypropylmethyl Cellulose Microparticles of Levodopa (and Carbidopa): In Vitro and Rat Model Kinetic Characteristics

• Main Authors: Benedicta Obenewaa Dankyi, MPhil (Author), Seth Kwabena Amponsah, PhD (Author), Grace Lovia Allotey-Babington, PhD (Author), Ismaila Adams, BPharm (Author), Nana Aboadwe Goode, BPharm (Author), Henry Nettey, PharmD/PhD (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: Background: Parkinson's disease is a neurodegenerative disorder, and a major cause of disability. Levodopa, a prodrug of dopamine, remains the gold standard in the pharmacological management of Parkinson's disease. Despite several attempts to improve the clinical efficacy of levo...