Triterpenic Acid Amides as a Promising Agent for Treatment of Metabolic Syndrome

• Главные авторы: Vladislav Fomenko (Автор), Mikhail Blokhin (Автор), Sergey Kuranov (Автор), Mikhail Khvostov (Автор), Dmitriy Baev (Автор), Marina S. Borisova (Автор), Olga Luzina (Автор), Tatyana G. Tolstikova (Автор), Nariman F. Salakhutdinov (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2020-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

A series of triterpenic acid amides were synthesized incorporating a 2-ethoxy-3-phenylpropanoic acid pharmacophore fragment. The synthesized compounds were tested for their ability to improve glycemic control and to counter lipid abnormalities in C57BL/6 mice placed on a high-fat/high-cholesterol di...