Triterpenic Acid Amides as a Promising Agent for Treatment of Metabolic Syndrome

• Main Authors: Vladislav Fomenko (Author), Mikhail Blokhin (Author), Sergey Kuranov (Author), Mikhail Khvostov (Author), Dmitriy Baev (Author), Marina S. Borisova (Author), Olga Luzina (Author), Tatyana G. Tolstikova (Author), Nariman F. Salakhutdinov (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of triterpenic acid amides were synthesized incorporating a 2-ethoxy-3-phenylpropanoic acid pharmacophore fragment. The synthesized compounds were tested for their ability to improve glycemic control and to counter lipid abnormalities in C57BL/6 mice placed on a high-fat/high-cholesterol di...