Triterpenic Acid Amides as a Promising Agent for Treatment of Metabolic Syndrome

• Váldodahkkit: Vladislav Fomenko (Dahkki), Mikhail Blokhin (Dahkki), Sergey Kuranov (Dahkki), Mikhail Khvostov (Dahkki), Dmitriy Baev (Dahkki), Marina S. Borisova (Dahkki), Olga Luzina (Dahkki), Tatyana G. Tolstikova (Dahkki), Nariman F. Salakhutdinov (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2020-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

A series of triterpenic acid amides were synthesized incorporating a 2-ethoxy-3-phenylpropanoic acid pharmacophore fragment. The synthesized compounds were tested for their ability to improve glycemic control and to counter lipid abnormalities in C57BL/6 mice placed on a high-fat/high-cholesterol di...