Proton Dependent Inhibition of the Cardiac Sodium Channel Nav1.5 by Ranolazine

• প্রধান লেখক: Stanislav eSokolov (লেখক), Colin H Peters (লেখক), Sridharan eRajamani (লেখক), Peter C Ruben (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2013-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Ranolazine is clinically approved for treatment of angina pectoris and is a potential candidate for antiarrhythmic, antiepileptic and analgesic applications. These therapeutic effects of ranolazine hinge on its ability to inhibit persistent or late Na+ currents in a variety of voltage-gated sodium c...