Phase 1 study to access safety, tolerability, pharmacokinetics, and pharmacodynamics of kynurenine in healthy volunteers

Abstract The kynurenine pathway (KP) is the main path for tryptophan metabolism, and it represents a multitude of potential sites for drug discovery in neuroscience, including pain, stroke, and epilepsy. L‐kynurenine (LKYN), the first active metabolite in the pathway, emerges to be a prodrug targeti...

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Main Authors: Mohammad Al‐Mahdi Al‐Karagholi (Author), Jakob Møller Hansen (Author), Dalia Abou‐Kassem (Author), Anna Koldbro Hansted (Author), Kumari Ubhayasekera (Author), Jonas Bergquist (Author), László Vécsei (Author), Inger Jansen‐Olesen (Author), Messoud Ashina (Author)
Format: Book
Published: Wiley, 2021-04-01T00:00:00Z.
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Call Number: A1234.567
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