Phase 1 study to access safety, tolerability, pharmacokinetics, and pharmacodynamics of kynurenine in healthy volunteers
Abstract The kynurenine pathway (KP) is the main path for tryptophan metabolism, and it represents a multitude of potential sites for drug discovery in neuroscience, including pain, stroke, and epilepsy. L‐kynurenine (LKYN), the first active metabolite in the pathway, emerges to be a prodrug targeti...
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Main Authors: | Mohammad Al‐Mahdi Al‐Karagholi (Author), Jakob Møller Hansen (Author), Dalia Abou‐Kassem (Author), Anna Koldbro Hansted (Author), Kumari Ubhayasekera (Author), Jonas Bergquist (Author), László Vécsei (Author), Inger Jansen‐Olesen (Author), Messoud Ashina (Author) |
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Format: | Book |
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Wiley,
2021-04-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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