Clinical variability in dystrophic epidermolysis bullosa and findings with scanning electron microscopy Variabilidade clínica em epidermólise bolhosa distrófica e achados de microscopia eletrônica de varredura

• Main Authors: Hiram Larangeira de Almeida Jr (Author), Luciane Maria Alves Monteiro (Author), Fernanda Mendes Goetze (Author), Ricardo Marques e Silva (Author), Nara Moreira Rocha (Author)
• Format: Book
• Published: Sociedade Brasileira de Dermatologia, 2012-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In dystrophic epidermolysis bullosa, the genetic defect of anchoring fibrils leads to cleavage beneath the basement membrane and its consequent loss. A 46 year-old female patient presented blisters with a pretibial distribution associated with nail dystrophy. Her two children had hyponychia and anon...