Formation and Physico-Chemical Evaluation of Nifedipine-hydroxypropyl-β-cyclodextrin and Nifedipine-methyl-β-cyclodextrin: The Development of Orodispersible Tablets

• Main Authors: Emma Adriana Ozon (Author), Marian Novac (Author), Daniela Gheorghe (Author), Adina Magdalena Musuc (Author), Mirela Adriana Mitu (Author), Iulian Sarbu (Author), Valentina Anuta (Author), Adriana Rusu (Author), Simona Petrescu (Author), Irina Atkinson (Author), Dumitru Lupuliasa (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The novelty in this study is the development of new orodispersible tablets containing nifedipine (NIF) as the active ingredient. Initially, the formation of inclusion complexes between nifedipine and two derivatives of beta-cyclodextrin, namely, hydroxypropyl-β-cyclodextrin (HP-β-CD) and methyl-β-cy...