Nrf2 participates in mechanisms for reducing the toxicity and enhancing the antitumour effect of Radix Tripterygium wilfordii to S180-bearing mice by herbal-processing technology

• Main Authors: Jun-Ming Wang (Author), Jin-Yang Li (Author), Hong Cai (Author), Rong-Xing Chen (Author), Yue-Yue Zhang (Author), Lu-Lu Zhang (Author), Ying Cui (Author), Yong-Xian Cheng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context: Radix Tripterygium wilfordii Hook. f. (Celastraceae) (LGT) has outstanding curative efficacy; however, side effects include high toxicity, particularly hepatotoxicity and nephrotoxicity. Objective: To investigate detoxification mechanisms of LGT through processing separately with each of th...