Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity

• Huvudskapare: Edanur Sen (Författare, medförfattare), Krishna P. Kota (Författare, medförfattare), Rekha G. Panchal (Författare, medförfattare), Sina Bavari (Författare, medförfattare), Erkan Kiris (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Botulinum neurotoxins (BoNTs) are known as the most potent bacterial toxins, which can cause potentially deadly disease botulism. BoNT Serotype A (BoNT/A) is the most studied serotype as it is responsible for most human botulism cases, and its formulations are extensively utilized in clinics for the...