Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity

• Автори: Edanur Sen (Автор), Krishna P. Kota (Автор), Rekha G. Panchal (Автор), Sina Bavari (Автор), Erkan Kiris (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Предмети: article
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Botulinum neurotoxins (BoNTs) are known as the most potent bacterial toxins, which can cause potentially deadly disease botulism. BoNT Serotype A (BoNT/A) is the most studied serotype as it is responsible for most human botulism cases, and its formulations are extensively utilized in clinics for the...