Resolvin D1 Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Inflammation, Oxidative and Endoplasmic Reticulum Stress

• Main Authors: Menglong Wang (Author), Jishou Zhang (Author), Mengmeng Zhao (Author), Jianfang Liu (Author), Jing Ye (Author), Yao Xu (Author), Zhen Wang (Author), Di Ye (Author), Dan Li (Author), Jun Wan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Resolvin D1 (RvD1) is a lipid mediator that promotes resolution of inflammation. However, the function of RvD1 in doxorubicin- (Dox-) induced cardiotoxicity remains to be clarified. This study aimed to investigate whether RvD1 could attenuate Dox-induced cardiac injury. The mice were divided into th...