Experimental infection of the pig with Mycobacterium ulcerans: a novel model for studying the pathogenesis of Buruli ulcer disease.

• Main Authors: Miriam Bolz (Author), Nicolas Ruggli (Author), Marie-Thérèse Ruf (Author), Meret E Ricklin (Author), Gert Zimmer (Author), Gerd Pluschke (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Buruli ulcer (BU) is a slowly progressing, necrotising disease of the skin caused by infection with Mycobacterium ulcerans. Non-ulcerative manifestations are nodules, plaques and oedema, which may progress to ulceration of large parts of the skin. Histopathologically, BU is characterized...