HDAC6 Inhibitors Rescued the Defective Axonal Mitochondrial Movement in Motor Neurons Derived from the Induced Pluripotent Stem Cells of Peripheral Neuropathy Patients with HSPB1 Mutation

The Charcot-Marie-Tooth disease 2F (CMT2F) and distal hereditary motor neuropathy 2B (dHMN2B) are caused by autosomal dominantly inherited mutations of the heat shock 27 kDa protein 1 (HSPB1) gene and there are no specific therapies available yet. Here, we assessed the potential therapeutic effect o...

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Main Authors: Ji-Yon Kim (Author), So-Youn Woo (Author), Young Bin Hong (Author), Heesun Choi (Author), Jisoo Kim (Author), Hyunjung Choi (Author), Inhee Mook-Jung (Author), Nina Ha (Author), Jangbeen Kyung (Author), Soo Kyung Koo (Author), Sung-Chul Jung (Author), Byung-Ok Choi (Author)
Format: Book
Published: Hindawi Limited, 2016-01-01T00:00:00Z.
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Call Number: A1234.567
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