The Bacterial Genomic Context of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases Highlights an Emerging Threat to Public Health

Type B dihydrofolate reductase (<i>dfrb</i>) genes were identified following the introduction of trimethoprim in the 1960s. Although they intrinsically confer resistance to trimethoprim (TMP) that is orders of magnitude greater than through other mechanisms, the distribution and prevalen...

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Main Authors: Claudèle Lemay- (Author), Sarah-Slim Diwan (Author), Joelle N. Pelletier (Author)
Format: Book
Published: MDPI AG, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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