GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models

• Main Authors: Yu Huang (Author), Jinyong Wang (Author), Xiling Wei (Author), Hui Zhang (Author), Wei Shang (Author), Xiangling Zhang (Author), Lanjiao Zhai (Author), Xi Chen (Author), Huiming Li (Author), Suofu Qin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cachexia is a complicated metabolic syndrome mainly associated with cancers, characterized by extreme weight loss and muscle wasting. It is a debilitating condition that negatively affects prognosis and survival. However, there is currently no effective pharmacological intervention that can reverse...