Antileishmanial Activity of 4,8-Dimethoxynaphthalenyl Chalcones on <i>Leishmania amazonensis</i>

• Main Authors: Kaio Maciel de Santiago-Silva (Author), Bruna Taciane da Silva Bortoleti (Author), Laudicéa do Nascimento Oliveira (Author), Fernanda Lima de Azevedo Maia (Author), Joyce Cristina Castro (Author), Ivete Conchon Costa (Author), Danielle Bidóia Lazarin (Author), James L. Wardell (Author), Solange M. S. V. Wardell (Author), Magaly Girão Albuquerque (Author), Camilo Henrique da Silva Lima (Author), Wander Rogério Pavanelli (Author), Marcelle de Lima Ferreira Bispo (Author), Raoni Schroeder B. Gonçalves (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmaniasis is a neglected tropical disease caused by <i>Leishmania</i> species. Available therapeutic options have several limitations. The drive to develop new, more potent, and selective antileishmanial agents is thus a major goal. Herein we report the synthesis and the biological a...