Protective effects of the selective alpha1A-adrenoceptor antagonist silodosin against cyclophosphamide-induced cystitis in rats

• Main Authors: Nanxi Liu (Author), Shogo Shimizu (Author), Takahiro Shimizu (Author), Kumiko Nakamura (Author), Masaki Yamamoto (Author), Youichirou Higashi (Author), Motoaki Saito (Author)
• Format: Book
• Published: Elsevier, 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the protective effects of a selective α1A-adrenoceptor antagonist, silodosin (Silod) on urinary bladder function in cyclophosphamide (CYP)-induced cystitis rats, with and without desensitization of the capsaicin (CAP)-sensitive afferent nerve pathway. Male Wistar rats (310-400 g) wer...