Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition

• Main Authors: Joseph M. Elsakr (Author), Jennifer C. Dunn (Author), Katherine Tennant (Author), Sifang Kathy Zhao (Author), Karly Kroeten (Author), Raymond C. Pasek (Author), Diana L. Takahashi (Author), Tyler A. Dean (Author), Digna R. Velez Edwards (Author), Carrie E. McCurdy (Author), Kjersti M. Aagaard (Author), Alvin C. Powers (Author), Jacob E. Friedman (Author), Paul Kievit (Author), Maureen Gannon (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: In humans, offspring of women who are overweight or obese are more likely to develop metabolic disease later in life. Studies in lower animal species reveal that a calorically-dense maternal diet is associated with alterations in islet cell mass and function. The long-term effects of mate...