Macrophages protect against loss of adipose tissue during cancer cachexia

• Main Authors: Merve Erdem (Author), Diana Möckel (Author), Sandra Jumpertz (Author), Cathleen John (Author), Athanassios Fragoulis (Author), Ines Rudolph (Author), Johanna Wulfmeier (Author), Jochen Springer (Author), Henrike Horn (Author), Marco Koch (Author), Georg Lurje (Author), Twan Lammers (Author), Steven Olde Damink (Author), Gregory van derKroft (Author), Felix Gremse (Author), Thorsten Cramer (Author)
• Format: Book
• Published: Wiley, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer cachexia represents a central obstacle in medical oncology as it is associated with poor therapy response and reduced overall survival. Systemic inflammation is considered to be a key driver of cancer cachexia; however, clinical studies with anti‐inflammatory drugs failed...